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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
20.3
Human Site:
S1488
Identified Species:
34.36
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
S1488
R
S
P
P
S
M
L
S
L
D
G
P
L
V
R
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
T1309
Y
A
L
A
V
K
P
T
P
P
A
P
A
L
R
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
S242
A
G
C
G
S
G
S
S
S
V
T
P
N
S
G
Dog
Lupus familis
XP_543382
1925
209302
S1491
R
S
P
P
A
V
L
S
L
D
G
P
L
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
S1551
R
S
P
P
S
M
L
S
L
D
G
P
L
V
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
Y313
H
Y
S
Q
D
S
G
Y
K
P
R
R
H
E
T
Chicken
Gallus gallus
Q5F3P8
2008
223067
S1594
R
S
P
P
S
V
L
S
L
D
M
Y
S
G
K
Frog
Xenopus laevis
Q66J90
1938
216239
A1531
G
P
K
K
P
L
A
A
H
E
F
E
A
C
V
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
E1419
S
F
P
A
S
P
K
E
L
P
V
P
M
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
T1258
P
S
G
K
V
N
E
T
K
N
I
L
K
R
E
Honey Bee
Apis mellifera
XP_395451
1406
159180
S1024
K
S
V
L
R
T
P
S
A
P
I
K
P
V
K
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
S1125
P
C
K
S
E
P
G
S
E
P
L
K
I
T
P
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
T1448
S
E
T
P
S
K
V
T
L
D
K
P
S
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
A931
F
E
R
E
A
L
R
A
A
G
I
E
D
I
E
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
13.3
20
86.6
N.A.
100
N.A.
N.A.
0
60
0
26.6
N.A.
6.6
20
6.6
33.3
P-Site Similarity:
100
33.3
20
100
N.A.
100
N.A.
N.A.
0
73.3
20
40
N.A.
20
33.3
13.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
15
15
0
8
15
15
0
8
0
15
0
0
% A
% Cys:
0
8
8
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
36
0
0
8
0
8
% D
% Glu:
0
15
0
8
8
0
8
8
8
8
0
15
0
8
15
% E
% Phe:
8
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
8
8
8
8
0
8
15
0
0
8
22
0
0
8
8
% G
% His:
8
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
22
0
8
15
0
% I
% Lys:
8
0
15
15
0
15
8
0
15
0
8
15
8
0
15
% K
% Leu:
0
0
8
8
0
15
29
0
43
0
8
8
22
15
0
% L
% Met:
0
0
0
0
0
15
0
0
0
0
8
0
8
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
8
0
0
8
0
0
% N
% Pro:
15
8
36
36
8
15
15
0
8
36
0
50
8
0
8
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
29
0
8
0
8
0
8
0
0
0
8
8
0
8
29
% R
% Ser:
15
43
8
8
43
8
8
50
8
0
0
0
15
8
8
% S
% Thr:
0
0
8
0
0
8
0
22
0
0
8
0
0
8
8
% T
% Val:
0
0
8
0
15
15
8
0
0
8
8
0
0
29
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
8
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _